Proteomics of In Vivo Models of Ischemic Stroke: A Systematic review with a Systems Biological Perspective

A total number of 534 deregulated proteins were manually extracted from the ivProt studies (n=130). Twenty-nine proteins were deregulated in more than one independent study. These proteins were grouped into 4 categories based on sample location, model type, occlusion/ reperfusion, and regulation- 1) Group I- Identical regulation with matched variables 2) Group II- Identical regulation with unmatched variables 3) Group III- Inconsistent regulation with matched models 4) Group IV- Inconsistent regulation with unmatched models. *Group IV has not been discussed in the main text.